Doxorubicin hydrochloride (adriamycin) cardiotoxicity evaluated by sequential radionuclide angiocardiography
نویسندگان
چکیده
منابع مشابه
Doxorubicin cardiotoxicity: prevention of congestive heart failure with serial cardiac function monitoring with equilibrium radionuclide angiocardiography in the current era.
BACKGROUND Congestive heart failure (CHF) is among the most serious toxicities of doxorubicin, a potent cancer chemotherapeutic agent. Serial left ventricular ejection fraction (LVEF) monitoring during doxorubicin therapy for preventing CHF was proposed over 20 years ago. The current utility and cost-effectiveness of this approach in the present era are not known. METHODS AND RESULTS Clinical...
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Two patients are described in whom intraventricular tumors were incidentally detected by radionuclide angiocardiography. This finding led, in one patient, to surgical cure.
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Planar equilibrium radionuclide angiography (ERNA) is used to determine global and regional measures of ventricular function (primarily left ventricular [LV] function) at rest and/or during exercise stress or pharmacologic intervention. These measures of ventricular function may include evaluations of ventricular wall motion, ejection fraction (EF), and other parameters of systolic and diastoli...
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Review of the radionuclide cardiac angiograms of 82 patients studied during the past year showed reflux of activity down the inferior vena cava in 7, all ofwhom had clinical evidencefor or clinical conditions associated with tricuspid regurgitation. Analysis of theflow of the radioactive bolus through the cardiac chambers demonstrates that the inferior vena cava fills only after activity enters...
متن کاملPrevention from Doxorubicin Cardiotoxicity by Available Protective Agents in Iran
Doxorubicin, used in pediatric chemotherapy regimens, has cardiotoxic effects. Dexrazoxane is co-administrated with doxorubicin to prevent its cardiotoxicity. Here we have explored some alternative food or drugs to be used in absence of dexrazoxane since it’s not readily available in Iran at this time. Keywords: Pediatric, chemotherapy, doxorubicin, cardiotoxicity, dexrazoxane, Iran.
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ژورنال
عنوان ژورنال: Cancer
سال: 1985
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19850701)56:1<76::aid-cncr2820560113>3.0.co;2-s